Antibody to CCDC104 is associated with a paraneoplastic antibody to CDR2 (anti-Yo)
نویسندگان
چکیده
منابع مشابه
a rare case of anti-yo antibody associated paraneoplastic sensory polyganglionopathy in a patient with ovarian cancer
paraneoplastic cerebellar degeneration is a rare, fatal neuronal syndrome associated with ovarian, breast and lung cancers. anti-yo antibody mediated paraneoplastic cerebellar degeneration is known to be associated with gynecological malignancies, especially ovarian cancer. however, there are no reports of anti-yo antibody associated predominant peripheral mixed sensory and motor neuropathy in ...
متن کاملRehabilitation for a patient with anti-Yo antibody-positive paraneoplastic cerebellar degeneration caused by breast cancer
RATIONALE Rehabilitation for paraneoplastic cerebellar degeneration (PCD) has been indicated as necessary. However, there are only a few reports on rehabilitation in PCD. We describe the course of physical and cognitive functions and activities of daily living (ADL) in a patient with PCD and examine the effect of rehabilitation, along with a review of relevant literature. PATIENT CONCERNS A 4...
متن کاملAnti-Yo antibody-mediated paraneoplastic cerebellar degeneration in a female patient with pleural malignant mesothelioma.
Paraneoplastic cerebellar degeneration is a rare non-metastatic complication of malignancies. It presents with acute or subacute onset of ataxia, dysarthria and intention tremor. Paraneoplastic cerebellar degeneration is most commonly associated with malignancies of the ovary, breast and lung. The anti-Yo (anti-Purkinje cells) antibodies that specifically damage the Purkinje cells of the cerebe...
متن کاملParaneoplastic cerebellar degeneration. I. A clinical analysis of 55 anti-Yo antibody-positive patients.
We reviewed the clinical findings in 55 patients with cerebellar degeneration associated with the anti-Yo antibody (an anti-Purkinje cell antibody identified in this study by histochemistry and Western blot). The patients were all women, 26 to 85 years old. Fifty-two of them proved to have malignancies, almost exclusively breast or gynecologic cancers and usually confined to the involved organs...
متن کاملParaneoplastic cerebellar degeneration with anti‐Yo antibodies – a review
The ataxic syndrome associated with Anti-Yo antibody, or Purkinje cell cytoplasmic antibody type 1 (PCA1), is the most common variant of paraneoplastic cerebellar degeneration (PCD). The typical presentation involves the subacute development of pancerebellar deficits with a clinical plateau within 6 months. The vast majority of cases have been reported in women with pelvic or breast tumors. Mag...
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ژورنال
عنوان ژورنال: Cancer Immunology, Immunotherapy
سال: 2009
ISSN: 0340-7004,1432-0851
DOI: 10.1007/s00262-009-0742-3